Understanding the Genetics of Extremophilic Archaea for the Exploitation of their Biotechnological Potential
　Project Title 　Understanding the Genetics of Extremophilic Archaea for the Exploitation of their
　Biotechnological Potential
　Project Manager 　Li Huang
　Telephone Number 　010-64807430
　E-MAIL 　huangl@sun.im.ac.cn
　Project Organization 　Institute of Microbiology,Chinese Academy of Sciences
　Collaborative Organization 　Institute of Plant Physiology and Ecology at Shanghai,
　Institute of Oceanography at Qingdao, CAS
　Research contents

This project involves a detailed analysis of molecular mechanisms underlining key steps in the genetic processes (e.g., DNA replication) and their control in extremophilic archaea (i.e., hyperthermophilic archaea, extremely halophilic archaea and their extrachromosomal genetic elements) through the use of biochemical, molecular biological, genetic and proteomic approaches.
　Anticipated objective

This project is expected to achieve the following goals:
(1) to increase our understanding of the molecular details of genetic processes, such as DNA replication, and their regulation in extremophilic Archaea;
(2) to construct molecular tools useful in the genetic manipulations of extremophilic Archaea;
(3) to generate knowledge and technologies for the exploitation of archaeal resources.
　Project Picture